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<big><center>[[Bacteria|'''BACK TO BACTERIA''']]</center></big>
 
<big><center>[[Bacteria|'''BACK TO BACTERIA''']]</center></big>
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==Clostridia==
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===Overview===
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*Organisms present in the soil, alimentary tract and faeces
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*Endospores may be present in liver and may be reactivated to cause disease
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*Neurotoxic clostridia, ''Clostridium tetani'' and ''Clostridium botulinum'' affect neuromuscular function but cause no tissue damage
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*Histotoxic clostridia cause localised lesions in tissues and may cause toxaemia
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*''C. perfringens'' cause inflammatory lesions in the gastrointestinal tract and enterotoxaemia
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===Characteristics===
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*Large Gram-positive rods
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*Obligate anaerobes
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*Fermentative, catalase negative, oxidase negative
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*Straight or slightly curved
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*Motile by flagellae
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*Require enriched media for growth
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*Produce endospores which vary in shape and location and cause bulging of mother cell
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===Pathogenesis and pathogenicity===
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*''C. perfringens'' colonies are surrounded by a zone of double haemolysis
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* ''Clostrisium'' bacteria are Gram-positive and obligate anaerobes.
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==Species==
      
===Clostridium botulinum===
 
===Clostridium botulinum===
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