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**Stiffness, localised spasms, altered heart and respiratory rates, dysphagia, altered facial expression, lock-jaw from mastigatory muscle spasm
 
**Stiffness, localised spasms, altered heart and respiratory rates, dysphagia, altered facial expression, lock-jaw from mastigatory muscle spasm
 
**Tonic muscle contraction easily stimulated
 
**Tonic muscle contraction easily stimulated
 
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*Treatment:
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**Antitoxin IV or into subarachnoid space on 3 consecutive days
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**Toxoid subcutaneously to promote active immune response
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**Penicillin to kill vegetative cells
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**Debridement and flushing of wound with hydrogen peroxide
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**Fluids, sedatives, muscle relaxants
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*Control:
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**Toxoid vaccine for farm animals
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**Debridement of wounds in horses
     
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