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**Stiffness, localised spasms, altered heart and respiratory rates, dysphagia, altered facial expression, lock-jaw from mastigatory muscle spasm
**Stiffness, localised spasms, altered heart and respiratory rates, dysphagia, altered facial expression, lock-jaw from mastigatory muscle spasm
**Tonic muscle contraction easily stimulated
**Tonic muscle contraction easily stimulated
*Treatment:
**Antitoxin IV or into subarachnoid space on 3 consecutive days
**Toxoid subcutaneously to promote active immune response
**Penicillin to kill vegetative cells
**Debridement and flushing of wound with hydrogen peroxide
**Fluids, sedatives, muscle relaxants
*Control:
**Toxoid vaccine for farm animals
**Debridement of wounds in horses