Changes

#'''The antibiotic with the narrowest antibacterial spectrum should be used.''' This will minimize the risk of development of resistant bacteria.

#'''The antibiotic with the narrowest antibacterial spectrum should be used.''' This will minimize the risk of development of resistant bacteria.

#'''Combinations of antibiotics are discouraged.''' The exception to this rule is the combination of amoxicillin or cephalosporins with metronidazole in severe mixed infections in which anaerobes are believed to play a major role.

#'''Combinations of antibiotics are discouraged.''' The exception to this rule is the combination of amoxicillin or cephalosporins with metronidazole in severe mixed infections in which anaerobes are believed to play a major role.

#'''A bactericidal antibiotic is preferable to a bacteriostatic agent'''. A bactericidal antibiotic (amoxicillin, cephalosporins and metronidazole) is preferred over a bacteriostatic antibiotic (clindamycin), mainly because there is less reliance on host inflammatory and immune reactions. Other considerations include the toxicity of the antibiotic and the patient’s history of previous allergic reactions to a particular antibiotic.

#'''A bactericidal antibiotic is preferable to a bacteriostatic agent'''. A bactericidal antibiotic (amoxicillin, cephalosporins and metronidazole) is preferable to a bacteriostatic antibiotic (clindamycin), mainly because there is less reliance on host inflammatory and immune reactions. Other considerations include the toxicity of the antibiotic and the patient’s history of previous allergic reactions to a particular antibiotic.

#'''The antibiotic of choice must be administered at the proper dose and correct time interval.''' Refer to a current compendium of data sheets for veterinary products for correct dosing and time interval. A seven-day course of antibiotics is generally recommended. Osteomyelitis generally requires a longer period of treatment. Suboptimal dosing and/or pulse therapy is not recommended.

#'''The antibiotic of choice must be administered at the proper dose and correct time interval.''' Refer to a current compendium of data sheets for veterinary products for correct dosing and time interval. A seven-day course of antibiotics is generally recommended. Osteomyelitis generally requires a longer period of treatment. Suboptimal dosing and/or pulse therapy is not recommended.

#'''The patient must be monitored for response to treatment and the potential development of adverse reactions.''' Re-evaluation of the diagnosis is required if there is no response to treatment. Culture and antibiogram may well be indicated. Minor adverse reactions, e.g. mild gastrointestinal side effects and inappetance, due to changes in the gut flora as a result of systemic treatment with amoxicillin and clindamycin, occasionally occur.

#'''The patient must be monitored for response to treatment and the potential development of adverse reactions.''' Re-evaluation of the diagnosis is required if there is no response to treatment. Culture and antibiogram may be indicated. Minor adverse reactions, e.g. mild gastrointestinal side effects and inappetance, due to changes in the gut flora as a result of systemic treatment with amoxicillin and clindamycin, occasionally occur.

==Summary==

==Summary==