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→Pathogenesis
==Pathogenesis==
==Pathogenesis==
Infection with ''Leishmania'' can produce either cutaneous or visceral disease as the infected macrophages proliferate in foci. The cutaneous form of the disease produces areas of ulceration on the pinnae of the [[Ear - Anatomy & Physiology|ears]], eyelids or on the [[Lips|lips]]. These ucerations can also be seen between the digits of the dogs paw. This is a parasitic infection of the [[Protozoal Dermatosis|skin]]. The visceral form causes a chronic wasting condition where generalised excema can be seen. Hair is lost from around the eyes giving the animal a 'spectacled' appearance. These symptoms are accompanied by an intermittent fever and some generalized lymphadenopathy.
Infection with ''Leishmania'' can produce either cutaneous or visceral disease as the infected macrophages proliferate in foci. The cutaneous form of the disease produces areas of ulceration on the pinnae of the [[Ear - Anatomy & Physiology|ears]], eyelids or on the [[Lips|lips]]. These ulcerations can also be seen between the digits of the dogs paw. This is a parasitic infection of the [[Protozoal Dermatosis|skin]]. The visceral form causes a chronic wasting condition where generalised excema can be seen. Hair is lost from around the eyes giving the animal a 'spectacled' appearance. These symptoms are accompanied by an intermittent fever and some generalized lymphadenopathy.
There is a very long incubation period from infection to pathology, which can take years and therefore many infected dogs either never become symptomatic or remain so for a long period of time. Even once an animal has been treated for leishmaniasis it is not uncommon for clinical symptoms to recur after a lengthy period of remission.
There is a very long incubation period from infection to pathology, which can take years and therefore many infected dogs either never become symptomatic or remain so for a long period of time. Even once an animal has been treated for leishmaniasis it is not uncommon for clinical symptoms to recur after a lengthy period of remission.