Changes

'''Mammogenesis'''

'''''Mammogenesis'''''

* Initial duct growth is stimulated by '''oestrogen''', '''growth hormone''' and '''glucocorticoids'''.

* Initial duct growth is stimulated by '''oestrogen''', '''growth hormone''' and '''glucocorticoids'''.

* '''Prolactin''' and '''progesterone''' are important for lobular alveolar growth.

* '''Prolactin''' and '''progesterone''' are important for lobular alveolar growth.

'''Lactogenesis and Galactopoesis'''

'''''Lactogenesis and Galactopoesis'''''

* Regulated by a '''lactogenic complex''' consisting of mainly prolactin and growth hormone, but also thyroid hormones, corticosteroids and insulin.   

* Regulated by a '''lactogenic complex''' consisting of mainly prolactin and growth hormone, but also thyroid hormones, corticosteroids and insulin.   

* '''Prolactin''' acts on mammary secretory epithelial cells to stimulate synthesis of milk proteins.  It is released during suckling and in response to the rise in oestrogen and glucocorticoids in parturition.

* '''Prolactin''' acts on mammary secretory epithelial cells to stimulate synthesis of milk proteins.  It is released during suckling and in response to the rise in oestrogen and glucocorticoids in parturition.

'''Milk Ejection Reflex'''

'''''Milk Ejection Reflex'''''

* '''Oxytocin''' is synthesised by magnocellar neurones of the '''Paraventricular nucleus (PVN)''' and '''Supraoptic nucleus (SON)''' of the '''hypothalamus'''.

* '''Oxytocin''' is synthesised by magnocellar neurones of the '''Paraventricular nucleus (PVN)''' and '''Supraoptic nucleus (SON)''' of the '''hypothalamus'''.

* Oxytocin is secreted from the '''posterior pituitary gland'''.

* Oxytocin is secreted from the '''posterior pituitary gland'''.