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==Alpha-casozepine==
==Alpha-casozepine==
Alpha-casozepine has been found to be extremely useful in the treatment of anxiety, where its efficacy has been shown to be on a par with selegiline<ref>Beata, C., Beaumont-Graff, E., Diaz, C., et al. Comparison of the effect of alpha-casozepine (Zylkene) versus selegiline hydrochloride on anxiety disorders in dogs. J Vet Behav 2007;2:175-83.</ref> as well as fear related behaviour<ref>Beata, C., Beaumont-Graff, E., Coll, V., et al. Effect of alpha-casozepine (Zylkene) on anxiety in cats. J Vet Behav 2007;2:40-6.</ref> in cats in conjunction with behavioural modification techniques. Alpha-casozepine is available as a supplement or as part of a commercial diet. It is a trypsin hydrolysate of alpha-S1 casein found in milk.
Alpha-casozepine has been found to be extremely useful in the treatment of anxiety, where its efficacy has been shown to be on a par with selegiline<ref>Beata, C., Beaumont-Graff, E., Diaz, C., et al. Comparison of the effect of alpha-casozepine (Zylkene) versus selegiline hydrochloride on anxiety disorders in dogs. J Vet Behav 2007;2:175-83.</ref> as well as fear related behaviour<ref>Beata, C., Beaumont-Graff, E., Coll, V., et al. Effect of alpha-casozepine (Zylkene) on anxiety in cats. J Vet Behav 2007;2:40-6.</ref> in cats in conjunction with behavioural modification techniques. Alpha-casozepine is available as a supplement or as part of a commercial diet. It is a trypsin hydrolysate of alpha-S1 casein found in milk.
==L-theanine==
==L-theanine==
Naturally found in green tea L-theanine is used to help treat anxiety. It is thought to increase GABA and block glutamate, therefore reducing its excitatory effects. In cats it has been used to treat behavioural problems including inappropriate elimination, fear and aggression both towards humans and other cats and has also been shown to help with the physical effects of anxiety<ref>6</ref>. To date there have been no drug interactions or side effects with use<ref>7</ref>. Benefits are usually seen approximately after 14-30 days of use.
==[[Melatonin]]==
==[[Melatonin]]==
There are reports that melatonin can be helpful in the treatment of anxiety, fear of loud noises<ref>Aronson, L. Animal behaviour case of the month. A dog was evaluated because of extreme fear. J Am Vet Med Assoc 1999;215:22-4.</ref> and problems with sleeping patterns in dogs and cats, however further research is needed to strengthen these claims and their level of effectiveness.
There are reports that melatonin can be helpful in the treatment of anxiety, fear of loud noises<ref>Aronson, L. Animal behaviour case of the month. A dog was evaluated because of extreme fear. J Am Vet Med Assoc 1999;215:22-4.</ref> and problems with sleeping patterns in dogs and cats, however further research is needed to strengthen these claims and their level of effectiveness.
==Tryptophan==
Tryptophan is an amino acid which is used to form serotonin. Low levels of tryptophan in the diet are thought to be linked to a fall in serotonin levels. This may have an affect on mood and can be used in alongside conventional pharmacological treatments, however care should be taken to look for any signs of serotonin syndrome. Studies have shown a reduction in behaviours related to stress and a decrease in signs of anxiety in cats supplemented with L-tryptophan<ref>Da Graca Pereira, G., Fragoso, S., L-tryptophan supplementation and its effect of multi-housed cats and working dogs. Proceedings of the 2010 European Veterinary Behaviour Meeting. Hamburg, 2010, 30-35.</ref><ref>Kato, M., Miyaji, K., Ohtani, N., et al. Effects of prescription diet on dealing with stressful situations and performance of anxiety-related behaviours in privately owned anxious dogs. 2012; 7:21-6</ref>Tryptophan can be added to the diet or is available at higher levels in some commercial diets.
==References==
==References==