Changes

==Medium Chain Triglycerides==

==Medium Chain Triglycerides==

In human Alzheimer's disease, CNS hypo metabolism may be a target for dietary therapy<ref>Costantini, L.C., Barr, L.J., Vogel, J.L., Henderson, S.T. (2008) Hypometabolism as a therapeutic target in Alzheimer's disease. BMC Neuroscience. 9(Suppl 2). S16.</ref>. Ketone bodies, such as beta-hydroxybutyrate, are a potential supplementary energy source for neurones, and support cells, with impaired oxidative phosphorulation systems. Supplementation with beta-hydroxybutyrate has been shown to improve cognition in human adults with memory impairment<ref>Reger, M.A., Henderson, S.T., Hale, C., Cholerton, B., Baker, L.D., Watson, G.S., Hyde, K., Chapman, D., Craft, S. (2004) Effects of Beta-hydroxybutyrate on cognition in memory-impaired adults. Neurobiology of Aging. 25. 311–314.</ref>. Medium chain triglycerides, which are metabolised to beta-hydroxybutyrate by the liver, have been shown to produce beneficial effects on the cognition of aged dogs<ref>Pan, Y., Larson, B., Araujo, J.A., Lau, W., de Rivera, C., Santana, R., Gore, A., Milgram, N.W. (2010) Dietary supplementation with medium-chain TAG has long-lasting cognition-enhancing effects in aged dogs. British Journal of Nutrition. 103. 1746–1754.</ref>.

In human Alzheimer's disease, CNS hypo metabolism may be a target for dietary therapy<ref>Costantini, L.C., Barr, L.J., Vogel, J.L., Henderson, S.T. (2008) Hypometabolism as a therapeutic target in Alzheimer's disease. BMC Neuroscience. 9(Suppl 2). S16.</ref>. Ketone bodies, such as beta-hydroxybutyrate, are a potential supplementary energy source for [[Neurons - Anatomy & Physiology|neurones]], and support cells, with impaired oxidative phosphorulation systems. Supplementation with beta-hydroxybutyrate has been shown to improve cognition in human adults with memory impairment<ref>Reger, M.A., Henderson, S.T., Hale, C., Cholerton, B., Baker, L.D., Watson, G.S., Hyde, K., Chapman, D., Craft, S. (2004) Effects of Beta-hydroxybutyrate on cognition in memory-impaired adults. Neurobiology of Aging. 25. 311–314.</ref>. Medium chain triglycerides, which are metabolised to beta-hydroxybutyrate by the liver, have been shown to produce beneficial effects on the cognition of aged dogs<ref>Pan, Y., Larson, B., Araujo, J.A., Lau, W., de Rivera, C., Santana, R., Gore, A., Milgram, N.W. (2010) Dietary supplementation with medium-chain TAG has long-lasting cognition-enhancing effects in aged dogs. British Journal of Nutrition. 103. 1746–1754.</ref>.

==References==

==References==