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Equine Pituitary Pars Intermedia Dysfunction (view source)
Revision as of 14:06, 30 March 2020
, 14:06, 30 March 2020→Diagnosis
'''Plasma cortisol concentration''' can be measured but there is a wide variation in normal values and it is not useful in diagnosing the condition.
'''Plasma cortisol concentration''' can be measured but there is a wide variation in normal values and it is not useful in diagnosing the condition.
'''The dexamethasone suppression test''' is the gold standard for diagnosis of the disease. Plasma cortisol samples are taken before and after dexamethasone administration. Normal horses will show a level of cortisol below 1 μg/dL 19 hours after dexamethasone administration, whereas affected horses will show a small degree of suppression in cortisol levels, but not to the level of normal horses, and levels also rebound more quickly.
outdated/no longer recommended --> '''The dexamethasone suppression test''' is the gold standard for diagnosis of the disease. Plasma cortisol samples are taken before and after dexamethasone administration. Normal horses will show a level of cortisol below 1 μg/dL 19 hours after dexamethasone administration, whereas affected horses will show a small degree of suppression in cortisol levels, but not to the level of normal horses, and levels also rebound more quickly.
A variety of other tests exist to evaluate horses for PPID:
A variety of other tests exist to evaluate horses for PPID: