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'''Plasma cortisol concentration''' can be measured but there is a wide variation in normal values and it is not useful in diagnosing the condition.
 
'''Plasma cortisol concentration''' can be measured but there is a wide variation in normal values and it is not useful in diagnosing the condition.
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outdated/no longer recommended --> '''The dexamethasone suppression test''' is the gold standard for diagnosis of the disease. Plasma cortisol samples are taken before and after dexamethasone administration. Normal horses will show a level of cortisol below 1 μg/dL 19 hours after dexamethasone administration, whereas affected horses will show a small degree of suppression in cortisol levels, but not to the level of normal horses, and levels also rebound more quickly.
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'''The dexamethasone suppression test''' is the gold standard for diagnosis of the disease. Plasma cortisol samples are taken before and after dexamethasone administration. Normal horses will show a level of cortisol below 1 μg/dL 19 hours after dexamethasone administration, whereas affected horses will show a small degree of suppression in cortisol levels, but not to the level of normal horses, and levels also rebound more quickly.
    
A variety of other tests exist to evaluate horses for PPID:
 
A variety of other tests exist to evaluate horses for PPID:
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