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Created page with "Triglycerides may be ingested or synthesised in the liver. They are complexed with cholesterol, phospholipids and plasma proteins to form lipoproteins. == Small Animals == Tr..."
Triglycerides may be ingested or synthesised in the liver. They are complexed with cholesterol, phospholipids and plasma proteins to form lipoproteins.
== Small Animals ==
Triglycerides are the main constituents of chylomicrons and very low density lipoproteins (VLDLs) which are responsible for the gross lipaemia seen in serum or plasma samples. Chylomicrons separate and form a fatty layer, after overnight refrigeration, whilst VLDLs remain dispersed in the serum/plasma. Where a sample is lipaemic after a 16 hour fast then a pathological lipaemia is thought to exist. Hyperlipidaemia refers to increased lipids (triglycerides, cholesterol or both) in the blood. Primary or secondary hyperlipidaemia is being increasingly recognised in dogs.
=== Cause of increased trigycerides ===
* Post prandial
* Hypothyroidism (dogs)
* Diabetes mellitus
* Hyperadrenocorticism
* Cholestasis (transient)
* Acute pancreatitis
* Feline idiopathic hyperchylomicronaemia
* Primary hyperlipidaemia in Miniature Schnauzer, Beagle, Shetland Sheep dog, Doberman, Rottweiler, Pyrenean Mountain dog
* Protein losing renal disorders including nephrotic syndrome
=== Complementary Tests ===
Cholesterol, thyroid panel, ACTH stimulation test or low dose dexamethasone screening test, glucose/fructosamine, lipase, PLI, urine protein:creatinine ratio and albumin.
== Equine ==
The reference interval for healthy horses is 0.07-0.61mmol/l. Healthy ponies and donkeys often have higher levels and some donkeys can see values up to 3.28mmol/l.
In all equines, an increased concentration of triglycerides (>5mmol/l) is consistent with a diagnosis of hyperlipidaemia. Hyperlipidaemia is seen in conditions which result in a negative energy balance for example, stress, pregnancy, malnutrition, lactation, endotoxaemia, renal failure. This is accentuated with obesity. It is harmless in most but pathological for a few. Ponies and females are more susceptible to the pathological syndrome, which can be fatal. Shetland ponies, other small ponies and donkeys appear prone.
=== Complementary Tests ===
Bile acids, liver enzymes, urea, creatinine and urine SG.
Test Codes - Please visit www.nwlabs.co.uk or see our current price list for more information
== Authors & References ==
[[NationWide Laboratories]]
== Small Animals ==
Triglycerides are the main constituents of chylomicrons and very low density lipoproteins (VLDLs) which are responsible for the gross lipaemia seen in serum or plasma samples. Chylomicrons separate and form a fatty layer, after overnight refrigeration, whilst VLDLs remain dispersed in the serum/plasma. Where a sample is lipaemic after a 16 hour fast then a pathological lipaemia is thought to exist. Hyperlipidaemia refers to increased lipids (triglycerides, cholesterol or both) in the blood. Primary or secondary hyperlipidaemia is being increasingly recognised in dogs.
=== Cause of increased trigycerides ===
* Post prandial
* Hypothyroidism (dogs)
* Diabetes mellitus
* Hyperadrenocorticism
* Cholestasis (transient)
* Acute pancreatitis
* Feline idiopathic hyperchylomicronaemia
* Primary hyperlipidaemia in Miniature Schnauzer, Beagle, Shetland Sheep dog, Doberman, Rottweiler, Pyrenean Mountain dog
* Protein losing renal disorders including nephrotic syndrome
=== Complementary Tests ===
Cholesterol, thyroid panel, ACTH stimulation test or low dose dexamethasone screening test, glucose/fructosamine, lipase, PLI, urine protein:creatinine ratio and albumin.
== Equine ==
The reference interval for healthy horses is 0.07-0.61mmol/l. Healthy ponies and donkeys often have higher levels and some donkeys can see values up to 3.28mmol/l.
In all equines, an increased concentration of triglycerides (>5mmol/l) is consistent with a diagnosis of hyperlipidaemia. Hyperlipidaemia is seen in conditions which result in a negative energy balance for example, stress, pregnancy, malnutrition, lactation, endotoxaemia, renal failure. This is accentuated with obesity. It is harmless in most but pathological for a few. Ponies and females are more susceptible to the pathological syndrome, which can be fatal. Shetland ponies, other small ponies and donkeys appear prone.
=== Complementary Tests ===
Bile acids, liver enzymes, urea, creatinine and urine SG.
Test Codes - Please visit www.nwlabs.co.uk or see our current price list for more information
== Authors & References ==
[[NationWide Laboratories]]