770 bytes added ,  16:16, 20 July 2008
no edit summary
Line 36: Line 36:  
*Cell wall proteins bind fibronectin and fibrinogen, allowing bacteria to attched to damaged tissues
 
*Cell wall proteins bind fibronectin and fibrinogen, allowing bacteria to attched to damaged tissues
 
*Coagulase, DNase and protein A production mark pathogenicity
 
*Coagulase, DNase and protein A production mark pathogenicity
*
+
*Haemolysins made by ''S. aureus'' and ''S. intermedius'' act as toxins
 +
*Alpha-haemolysin prouces a narrow zone of complete haemolysis; this toxin causes necrosis and targets mast cells and plasma cells, whose contents cause damage
 +
*Beta-haemolysin produces a wide zone of incomplete haemolysis; damages membranes and causes leakage, contributing to necrosis
 +
*Also gamma and delta toxins
 +
*Toxic shock syndrome toxin acts as a superantigen, which causes T cell proliferation and production of cytokines, leading to cardiovascular shock, with microthrombus formation in capillaries
 +
*Enterotoxins produced by some strains of ''S. aureus'' cause food poisoning in humans
 +
*Proteases, hyaluronidases and lipases facilitate survival of bacteria and spread and tissue destruction
    
===Diagnosis===
 
===Diagnosis===
462

edits