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Fish - Inducing Reproduction - Anatomy & Physiology (view source)
Revision as of 07:13, 30 July 2008
, 07:13, 30 July 2008→GnRH Analogue with Dopamine Antagonist
== GnRH Analogue with Dopamine Antagonist ==
== GnRH Analogue with Dopamine Antagonist ==
* Leutinizing Hormone Releasing Hormone (LHRH) is the name of a mammalian hormone that has been employed successfully to induce the reproductive hormonal cascade.
* Recently, synthetic analogues of LHRH ('''LHRHa''') have been developed that are more effective.
** More pure and are not rapidly metabolized by fish.
** Remain active for longer periods.
* Under natural conditions, there is a feedback mechanism in fish that limits the release of gonadotropin.
* This mechanism uses dopamine, which inhibits the action of LHRH.
* When dopamine is present in the fish, even LHRHa will have only limited success.
* A dopamine antagonist is often used to limit the effects of dopamine.
* When LHRHa and a dopamine antagonist are used in conjunction, reproductive success dramatically increases.