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Joints Inflammatory - Pathology (view source)

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**Morbidity up tp 50%

**Affects mostly unthrifty lmbs

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**Fibrosis and [[Musculoskeletal ~~terminology~~|osteophyte]] formation in later stages -> persistent lameness

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**Fibrosis and [[Musculoskeletal Terminology - Pathology|osteophyte]] formation in later stages -> persistent lameness

*[[Corynebacterium species|'''''Corynebacterium pyogenes''''']]

**May cause post-dipping joint infections

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**Chronic stage

***More commonly encountered

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***Erosion of articular surface of joints with formation of [[Musculoskeletal ~~terminology~~|pannus +/- joint ankylosis]]

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***Erosion of articular surface of joints with formation of [[Musculoskeletal Terminology - Pathology|pannus +/- joint ankylosis]]

***Vaccination prevents septicaemic and urticarial forms but has no effect on joints

****Probably due to dead bacteria still stimulating host immune system

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***Mineralisation

***Mononuclear cell infiltration

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***[[Musculoskeletal ~~terminology~~|Pannus]] formation

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***[[Musculoskeletal Terminology - Pathology|Pannus]] formation

***[[Joints - normal#Articular cartilage|Articular cartilage]] destruction

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**Marked villus hypertrophy of synovial membrane

**Cartilage erosion

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**[[Musculoskeletal ~~terminology~~|Pannus and periarticular osteophyte]] formation

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**[[Musculoskeletal Terminology - Pathology|Pannus and periarticular osteophyte]] formation

**In severe cases ankylosis

*Histologically:

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