Changes

===Ventricular Septation===

===Ventricular Septation===

The first sign of ventricular septation is the bulboventricular septum, which separates the dilated portion of the bulbus cordis (primordial right ventricle) from the embryonic ventricle (primordial left ventricle). The bulboventricular septum exists as a muscular fold and forms the primitive interventricular septum. Continued growth results in enlargement of the ventricles and subsequent lengthening of the interventricular septum. The interventricular foramen finally closes as a consequence of differential cellular proliferation.

Expansion of the ventricular myocardium results in the formation of the interventricualr groove at the interface of the right and left ventricles. As growth continues the muscles push together forming a fold, this is the primitive interventricular septum. Continued growth results in enlargement of the ventricles and subsequent lengthening of the interventricular septum. The Interventricualr septum extends towards the Septum Intermedium but does not fuse, leaving a gap called the interventricualr foramen. The interventricular foramen finally closes as a consequence of differential cellular proliferation.

Further information on development of the heart can be found [http://www.meddean.luc.edu/lumen/MedEd/GrossAnatomy/thorax0/heartdev/main_fra.html here]

Further information on development of the heart can be found [http://www.meddean.luc.edu/lumen/MedEd/GrossAnatomy/thorax0/heartdev/main_fra.html here]