The primordium of the heart forms in the cardiogenic plate located at the cranial end of the embryo. These angiogenic cells are derived from the lateral plate [http://w01.rvcwiki.wf.ulcc.ac.uk/index.php/Developmental_Biology_-_Gastrulation_-_Anatomy_%26_Physiology#Introduction Mesoderm] The Angiogenic cell clusters lie in a horseshoe shape configuration in the plate and coalesce to form two endocardial tubes. These tubes are then forced into the thoracic region due to cephalic and lateral foldings where they fuse together forming a single endocardial tube. | The primordium of the heart forms in the cardiogenic plate located at the cranial end of the embryo. These angiogenic cells are derived from the lateral plate [http://w01.rvcwiki.wf.ulcc.ac.uk/index.php/Developmental_Biology_-_Gastrulation_-_Anatomy_%26_Physiology#Introduction Mesoderm] The Angiogenic cell clusters lie in a horseshoe shape configuration in the plate and coalesce to form two endocardial tubes. These tubes are then forced into the thoracic region due to cephalic and lateral foldings where they fuse together forming a single endocardial tube. |