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Type I Hypersensitivity
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Revision as of 15:13, 29 August 2008
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15:13, 29 August 2008
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==Introduction==
==Introduction==
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* Also known as IgE-mediated or anaphylactic hypersensitivity.
+
* Also known as
[[Immunoglobulin E - WikiBlood|
IgE
]]
-mediated or anaphylactic hypersensitivity.
* Ranges from mild cases, such as hayfever, to life-threatening reactions, such as bee-stings.
* Ranges from mild cases, such as hayfever, to life-threatening reactions, such as bee-stings.
* Antigens that induce a type I reaction are known as allergens.
* Antigens that induce a type I reaction are known as allergens.
* Generally affects face, eyes, nose and feet
* Generally affects face, eyes, nose and feet
−
* IgE has a high affinity to IgE receptors on mast cells and basophils, and so binds these receptors.
+
*
[[Immunoglobulin E - WikiBlood|
IgE
]]
has a high affinity to IgE receptors on mast cells and basophils, and so binds these receptors.
−
==Common allergens which elict a type I hypersensitivity reaction:==
==Common allergens which elict a type I hypersensitivity reaction:==
Mmadment
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