Changes

==Introduction==

==Introduction==

The endoderm will form the lining of the gut and the organs that develop from it. Splanchnic mesoderm surrounds the endoderm and orginates from the lateral plate mesoderm. It will form the smooth [[Muscles muscle]] of the gut that are used for peristalsis.

The endoderm will form the lining of the gut and the organs that develop from it. Splanchnic mesoderm surrounds the endoderm and orginates from the lateral plate mesoderm. It will form the smooth [[Muscles and Tendons - Anatomy & Physiology|muscle]] of the gut that are used for peristalsis.

==Endoderm Development==

==Endoderm Development==

==Regionalisation of the Gut==

==Regionalisation of the Gut==

*The gut tube will develop into the oesophagus; stomach; small intestine; large intestine; and anus.

*The gut tube will develop into the [[Oesophagus - Anatomy & Physiology|oesophagus]]; [[Forestomach - Anatomy & Physiology|stomach]]; [[Small Intestine - Anatomy & Physiology|small intestine]]; [[Large Intestine - Anatomy & Physiology|large intestine]]; and [[Anus - Anatomy & Physiology|anus]].

*Regionalisation of these tissues occurs through co-ordinated endoderm and splanchnic mesoderm develop.

*Regionalisation of these tissues occurs through co-ordinated endoderm and splanchnic mesoderm develop.

*The endoderm governs splanchnic mesoderm development by releasing a signalling factor (sonic hedgehog) which induces differential mesoderm development.

*The endoderm governs splanchnic mesoderm development by releasing a signalling factor (sonic hedgehog) which induces differential mesoderm development.