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New page: {{toplink |backcolour =CDE472 |linkpage =Musculoskeletal System - Pathology |linktext =Musculoskeletal System |maplink = Musculoskeletal System (Content Map) - Pathology |pagetype =Patholo...
{{toplink
|backcolour =CDE472
|linkpage =Musculoskeletal System - Pathology
|linktext =Musculoskeletal System
|maplink = Musculoskeletal System (Content Map) - Pathology
|pagetype =Pathology
|sublink1=Muscles Degenerative - Pathology
|subtext1=MUSCLES DEGENERATIVE
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Zenker degeneration describes partial degeneration of the muscle fibre. The fibre may regenerate of the sarcolemma remains intact.
Initially there is loss of striations and hyaline change is visible histologically. The fibre will then fragment and some fragments will accumulate calcium which stains basophilic. Macrophages invade the fibres to phagocytose the degenerate muscle proteins.
If the sarcolemma is damaged then repair of the defect is by fibrosis.
|backcolour =CDE472
|linkpage =Musculoskeletal System - Pathology
|linktext =Musculoskeletal System
|maplink = Musculoskeletal System (Content Map) - Pathology
|pagetype =Pathology
|sublink1=Muscles Degenerative - Pathology
|subtext1=MUSCLES DEGENERATIVE
}}
<br>
Zenker degeneration describes partial degeneration of the muscle fibre. The fibre may regenerate of the sarcolemma remains intact.
Initially there is loss of striations and hyaline change is visible histologically. The fibre will then fragment and some fragments will accumulate calcium which stains basophilic. Macrophages invade the fibres to phagocytose the degenerate muscle proteins.
If the sarcolemma is damaged then repair of the defect is by fibrosis.