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Immunodeficiencies - WikiBlood (view source)
Revision as of 14:29, 8 September 2008
, 14:29, 8 September 2008→Canine X-Linked Severe Combined Immune Deficiency (Canine SCID)
*X-linked recessive defect in the gene conding for the IL-2 receptor
*X-linked recessive defect in the gene conding for the IL-2 receptor
**IL-2 receptor is a receptor for the cytokine IL-2 which causes [[Lymphocytes - WikiBlood#T cells|T cells]] to proliferate
**IL-2 receptor is a receptor for the cytokine IL-2 which causes [[Lymphocytes - WikiBlood#T cells|T cells]] to proliferate
*Causes lymphoid hypoplasia, stunted growth and increses the animal's susceptibility to infection
*Causes lymphoid hypoplasia, stunted growth and increases the animal's susceptibility to infection
*Animal usually dies from pneumonia or sepsis as the level of maternal [[Immunoglobulins - WikiBlood|antibody]] decreases
*Animal usually dies from pneumonia or sepsis as the level of maternal [[Immunoglobulins - WikiBlood|antibody]] decreases