Line 30: Line 30:     
===Deficiencies of Innate Immunity===
 
===Deficiencies of Innate Immunity===
 
+
[[Image:Grey Collie Syndrome.jpg|thumb|right|150px|Appearance of a puppy with Grey Collie syndrome - Copyright Michelle Tennis & Peggy Melton]]
 
====Canine Cyclic Haematopoiesis====
 
====Canine Cyclic Haematopoiesis====
 
*Also called '''Grey Collie Syndrome'''
 
*Also called '''Grey Collie Syndrome'''
Line 37: Line 37:  
*Diluted grey coat colour, stunted growth, poor wound healing
 
*Diluted grey coat colour, stunted growth, poor wound healing
 
*Neutropenia every 2 weeks which lasts 3-4 days due to cyclic production of cells from [[Bone Marrow - Anatomy & Physiology|bone marrow]]
 
*Neutropenia every 2 weeks which lasts 3-4 days due to cyclic production of cells from [[Bone Marrow - Anatomy & Physiology|bone marrow]]
*Recurrent infections, e.g. pyrexia, [[Intestine Diarrhoea - Pathology|diarrhoea]], gingivitis and arthritis
+
*Animals are prone to recurrent infections, mainly from the respiratory and gastrointestinal tract
 +
**E.g. pyrexia, [[Intestine Diarrhoea - Pathology|diarrhoea]], gingivitis and arthritis
 +
*Puppies can be distinguised from other litter mates by the diluted grey collouring
 +
*Affected puppies show symptoms such as fever, joint pain and eye, skin and respiratory infections from 8 weeks of age
 +
*Affected animals rarely live beyond 2-3 years with most puppies dying withing a few weeks of birth
    
====Canine Leukocyte Adhesion Deficiency (CLAD)====
 
====Canine Leukocyte Adhesion Deficiency (CLAD)====
3,326

edits