The idea behind this is that you measure factors which would normally be excreted. The same idea is behind the measurement of endogenous creatinine. However this is not ideal as it is altered by non-renal factors and they only change when the renal failure is very advanced as there is a large functional reserve in the kidneys. Urea is also not idea in horses and ruminants as it is used by the digestive micro flora to make microbial protein. | The idea behind this is that you measure factors which would normally be excreted. The same idea is behind the measurement of endogenous creatinine. However this is not ideal as it is altered by non-renal factors and they only change when the renal failure is very advanced as there is a large functional reserve in the kidneys. Urea is also not idea in horses and ruminants as it is used by the digestive micro flora to make microbial protein. |