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Scrapie is a neurological disease of sheep first recorded in 1732. Clinical signs include progressive ataxia and pruritis. Histology shows vacuolation of CNS (brain and spinal cord). Agent of disease is a prion, which is a transmissible, infectious protein with an abnormal folding structure.
Scrapie is a neurological disease of sheep first recorded in 1732. Clinical signs include progressive ataxia and pruritis. Histology shows vacuolation of CNS (brain and spinal cord). Agent of disease is a prion, which is a transmissible, infectious protein with an abnormal folding structure.