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Sheep Pulmonary Adenomatosis (view source)
Revision as of 19:35, 18 October 2008
, 19:35, 18 October 2008New page: {{unfinished}} {{toplink |linkpage =Viruses |linktext =VIRUSES |sublink1=Retroviridae |subtext1=RETROVIRIDAE |pagetype =Bugs }} <br> ====Antigenicity==== *The virus cannot be grown in cu...
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{{toplink
|linkpage =Viruses
|linktext =VIRUSES
|sublink1=Retroviridae
|subtext1=RETROVIRIDAE
|pagetype =Bugs
}}
<br>
====Antigenicity====
*The virus cannot be grown in culture, although it can be seen by EM on tumor cells of infected sheep
====Pathogenesis====
*Causes a proliferation of alveolar lining cells, producing massive amounts of fluid
*Proliferative foci project into alveoli and bronchi and from slow-growing tumors
*Death occurs between 3-4 years of age
Clinical signs:
*Low exercise tolerance
*Gradual weight loss
*Dyspnoea
*Coughing
*Nasal fluid discharges during wheelbarrow test
*Secondary bacterial infection by ''Pasteurella hemolytica'' often precipitates death
*PM reveals fawn-gray tumor
====Epidemiology====
*Found in 25% of pneumonia cases in Scotland
*Absent in USA, common in UK
====Diagnosis====
*Electron microscopy on lung biopsy
====Control====
*Cull clinically affected animals
{{toplink
|linkpage =Viruses
|linktext =VIRUSES
|sublink1=Retroviridae
|subtext1=RETROVIRIDAE
|pagetype =Bugs
}}
<br>
====Antigenicity====
*The virus cannot be grown in culture, although it can be seen by EM on tumor cells of infected sheep
====Pathogenesis====
*Causes a proliferation of alveolar lining cells, producing massive amounts of fluid
*Proliferative foci project into alveoli and bronchi and from slow-growing tumors
*Death occurs between 3-4 years of age
Clinical signs:
*Low exercise tolerance
*Gradual weight loss
*Dyspnoea
*Coughing
*Nasal fluid discharges during wheelbarrow test
*Secondary bacterial infection by ''Pasteurella hemolytica'' often precipitates death
*PM reveals fawn-gray tumor
====Epidemiology====
*Found in 25% of pneumonia cases in Scotland
*Absent in USA, common in UK
====Diagnosis====
*Electron microscopy on lung biopsy
====Control====
*Cull clinically affected animals