Changes

==Pharmacokinetic Considerations==

==Pharmacokinetic Considerations==

They are small, lipid soluble molecules that are readily absorbed by the gastrointestinal tract. As such they have fantastic tissue penetration and can enter exclusive tissue such as the brain and the CSF.

They are small, lipid soluble molecules that are readily absorbed by the gastrointestinal tract. As such they have fantastic tissue penetration and can enter exclusive tissue such as the brain and the CSF. It is metabolised in the liver and 2/3 of the dose is then excreted in urine.

 

==Side Effects and Contraindications==

==Side Effects and Contraindications==