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New page: {{unfinished}} {{toplink |linkpage =Viruses |linktext =VIRUSES |sublink1=Herpesviridae |subtext1=HERPESVIRUSES |pagetype =Bugs }} <br> ====Hosts==== *The most important disease of '''un...
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{{toplink
|linkpage =Viruses
|linktext =VIRUSES
|sublink1=Herpesviridae
|subtext1=HERPESVIRUSES
|pagetype =Bugs
}}
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====Hosts====
*The most important disease of '''unvaccinated backyard chicken flocks'''

====Pathogenesis====
*Replicates initially in the lungs and B cells
*Enters feather follicles: produces virus-laden dander that is shed into litter
*Reaches T cells, causing proliferation without virus protein production
*T cells localize in brain or nerves causing '''encephalitis'''
*End stage: massive visceral tumors

====Epidemiology====
*More virulent strains evolving: presents a challenge to vaccinal immunity

====Control====
*Removal of litter between batches of chicks
*'''Vaccines''' administered in ovo at 18 days
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