225
edits
Changes
no edit summary
==Local Anaesthetic Agents==
==Local Anaesthetic Agents==
There are a variety of drugs available to use for local analgesia/anaesthesia. They vary in duration of action, but all act in a similar way. Lipid solubility determines the potency of the agent, while the protein binding ability is thought to determine the duration of action. The preparation is also important, as some preprations cannot be used for certain blocks or in certain regions of the body, for example for epidurals, only preservative free preparations can be used.
There are a variety of drugs available to use for local analgesia/anaesthesia. They vary in duration of action, but all act in a similar way. Lipid solubility determines the potency of the agent, while the protein binding ability is thought to determine the duration of action. The preparation is also important, as some preprations cannot be used for certain blocks or in certain regions of the body, for example for epidurals, only preservative free preparations can be used.
Care should be taken when using local anaesthetic agents that doses are kept as low as possible to avoid toxicity problems.