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*May be a primary pathogen or opportunistic
 
*May be a primary pathogen or opportunistic
   −
*Targets the respiratory system
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*Targets the [[Cardiorespiratory System - Anatomy & Physiology|respiratory system]]
**Including the paranasal sinuses
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**Including the [[Paranasal sinuses - Anatomy & Physiology|paranasal sinuses]]
 
**Also can be systemic, cutaneous, visceral, skeletal or ocular
 
**Also can be systemic, cutaneous, visceral, skeletal or ocular
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**Can spread within the herd
 
**Can spread within the herd
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*Affects the CNS of dogs and cats
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*Affects the [[Nervous System - CNS - Anatomy & Physiology|CNS]] of dogs and cats
**Paranasal sinuses and pharynx can be infected with dissemination to the CNS and other tissues
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**[[Paranasal sinuses - Anatomy & Physiology|paranasal sinuses]] and [[Pharynx - Anatomy & Physiology|pharynx]] can be infected with dissemination to the [[Nervous System - CNS - Anatomy & Physiology|CNS]] and other tissues
***E.g. Lungs, kidneys and joints
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***E.g. [[Lungs - Anatomy & Physiology|Lungs]], [[Urinary System - Anatomy & Physiology#The Kidney|kidneys]] and [[Joints - Anatomy & Physiology|joints]]
 
**Also causes subcutaneous granulomas
 
**Also causes subcutaneous granulomas
 
**The tip of the nose is a common site of infection in cats
 
**The tip of the nose is a common site of infection in cats
 
***See [[Respiratory Fungal Infections - Pathology#In Cats|here]]
 
***See [[Respiratory Fungal Infections - Pathology#In Cats|here]]
   −
*Causes myxoma-like lesions of the lung and lip in horses
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*Causes myxoma-like lesions of the [[Lungs - Anatomy & Physiology|lung]] and [[Lips - Anatomy & Physiology|lip]] in horses
    
*Causes cryptococcal meningitis in humans
 
*Causes cryptococcal meningitis in humans
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*Gram positive
 
*Gram positive
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*Grows on blood agar and Sabouraud's Dextrose agar forming white, granular colonies which become slimy, mucoid and turn cream/brown within a week
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*Grows on blood agar and Sabouraud's Dextrose agar forming white, granular colonies which become slimy, mucoid and turn creamy/brown within a week
    
*Species identified by carbohydrate assimilation tests
 
*Species identified by carbohydrate assimilation tests
   −
*Antigen and antibody should be tested for as antibody formed by the body is soon overwhelmed and neutralised by abundent polysaccharide antigen from the capsule, in active, systemic infections
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*Antigen and antibody should be tested for as [[Immunoglobulins - WikiBlood|antibody]] formed by the body is soon overwhelmed and neutralised by abundent polysaccharide antigen from the capsule in active, systemic infections
**Latex agglutination for antigen, complement fixation, ELISA and IFAT can be used
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**Latex agglutination for [[Adaptive Immune System - WikiBlood#Actions of the Adaptive Immune System|antigen]], complement fixation, ELISA and IFAT can be used
    
==Geotrichosis==
 
==Geotrichosis==
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