Changes

*Mild neutrophilia with left shift.

*Mild neutrophilia with left shift.

*Increased alanine aminotransferase (ALT)

*Increased alanine aminotransferase (ALT)

*Normaly to slightly increased alkaline phosphatase (ALP)

*Normally to slightly increased alkaline phosphatase (ALP)

*Normal to slightly increased total bilirubin concentration

*Normal to slightly increased total bilirubin concentration

**Selected antibiotic should be excreted in the bile in active form, and should be active against aerobic and anaerobic intestinal coliforms.   

**Selected antibiotic should be excreted in the bile in active form, and should be active against aerobic and anaerobic intestinal coliforms.   

**Amoxicillin potentiated with clavulanic acid at 15-20 mg/kg PO q8 hours is a good initial choice.

**Amoxicillin potentiated with clavulanic acid at 15-20 mg/kg PO q8 hours is a good initial choice.

**Metronidazol may be added to extend the spectrum of anaerobes and coliforms.

**Metronidazole may be added to extend the spectrum of anaerobes and coliforms.

*Surgery is warranted if discrete choleliths or complete biliary obstruction is identified.   

*Surgery is warranted if discrete choleliths or complete biliary obstruction is identified.   

**In cases of complete extrahepatic biliary obstruction, surgical decompression and cholecystoduodenostomy or cholecystojejunostomy should be performed.

**In cases of complete extrahepatic biliary obstruction, surgical decompression and cholecystoduodenostomy or cholecystojejunostomy should be performed.

==References==

==References==

*Marks, S.L. (2003). Update on the Diagnosis and Management of Feline Cholangiohepatitis. ''Waltham Feline Medicine Symposium''

*Marks, S.L. (2003). Update on the Diagnosis and Management of Feline Cholangiohepatitis. ''Waltham Feline Medicine Symposium''.