Changes

===Paraneoplastic Syndromes===

===Paraneoplastic Syndromes===

* Hypercalcaemia - may be associated with lymphoma

* Hypercalcaemia - may be associated with lymphoma

* Hypoglycaemia - can be associated with leiomyomas and leiomyosarcomas

* Hypoglycaemia - can be associated with leiomyomas and leiomyosarcomas and is potentially reversibe following tumour resection.

==Treatment==

==Treatment==

===Radiotherapy===

===Radiotherapy===

Unreported

Unreported. Surrounding tissues including the liver and intestine show poor tolerance.

===Other Medical Management===

===Other Medical Management===

Symptomatic therapy of for example vomiting may improve quality of life in the short term - treatment options include anti-emetics such as metocolpramide and H2 blockers including ranitidine and cimetidine.

Symptomatic therapy of for example vomiting may improve quality of life in the short term - treatment options include anti-emetics such as metocolpramide and H2 blockers including ranitidine and cimetidine. Inhibitors of c-Kit e.g imatinib have been used in humans with GIST tumours. Such inhibitors may be useful for GIST in animals.  

==Prognosis==

==Prognosis==

* Benign tumours - Frequently cured by surgical resection. Prognosis good.

* Benign tumours - Frequently cured by surgical resection. Prognosis good.

* Lymphoma - response to chemotherapy usually poor. Survival rates low.

* Lymphoma - response to chemotherapy usually poor. Survival rates low.

* Most malignant tumours - usually associated with recurrent or metastatic disease. Prognosis therefore usually poor despite surgical resection. Survival time up to six months.

* Most malignant tumours - usually associated with recurrent or metastatic cancer. Prognosis therefore usually poor despite surgical resection. Survival time up to six months.

* Extramedullary plasmacytomas - can have a very good prognosis following surgery and chemotherapy.

==References==

==References==