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Immunodeficiencies - WikiBlood
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Revision as of 10:33, 14 August 2009
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10:33, 14 August 2009
→Canine X-Linked Severe Combined Immune Deficiency (Canine SCID)
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====Canine X-Linked Severe Combined Immune Deficiency (Canine SCID)====
====Canine X-Linked Severe Combined Immune Deficiency (Canine SCID)====
*Affects Basset Hounds and Corgis
*Affects Basset Hounds and Corgis
−
*X-linked recessive defect in the gene
conding
for the IL-2 receptor
+
*X-linked recessive defect in the gene
coding
for the IL-2 receptor
**IL-2 receptor is a receptor for the cytokine IL-2 which causes [[Lymphocytes - WikiBlood#T cells|T cells]] to proliferate
**IL-2 receptor is a receptor for the cytokine IL-2 which causes [[Lymphocytes - WikiBlood#T cells|T cells]] to proliferate
*Causes lymphoid hypoplasia, stunted growth and increases the animal's susceptibility to infection
*Causes lymphoid hypoplasia, stunted growth and increases the animal's susceptibility to infection
Kwhittle
273
edits