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Also known as ''lymphocytic-plasmacytic cholangitis or cholangiohepatitis'', ''lymphocytic portal hepatitis'' and ''non-suppurative cholangitis or cholangiohepatitis''.

Also known as ''lymphocytic-plasmacytic cholangitis or cholangiohepatitis'', ''lymphocytic portal hepatitis'' and ''non-suppurative cholangitis or cholangiohepatitis''.

==Signalment==

==Signalment==

*Young to middle-aged cats, 50% under 4 years old.

*Young to middle-aged cats, 50% under 4 years old.

==Description==

==Description==

'''Lymphocytic cholangitis''' is a slowly progressive chronic disease characterised by infiltration of the portal areas of the liver with inflammatory cells, mostly [[Lymphocytes - WikiBlood|lymphocytes]] and [[B cell differentiation - WikiBlood#Plasma cells|plasma cells]].  Bile duct hypertrophy and [[Liver General Pathology - Pathology#Fibrosis - Repair|fibrosis]] are present.  However, lymphocytic cholangitis does not progress to biliary [[Liver General Pathology - Pathology#Cirrhosis|cirrhosis]].  An immune-mediated aetiology has been postulated but this has not been substantiated to date.  It is rarely associated with [[Pancreatitis - WikiClinical|pancreatitis]], compared to [[Neutrophilic Cholangitis]]

'''Lymphocytic cholangitis''' is a slowly progressive chronic disease characterised by infiltration of the portal areas of the liver with inflammatory cells, mostly [[Lymphocytes - WikiBlood|lymphocytes]] and [[B cell differentiation - WikiBlood#Plasma cells|plasma cells]].  Bile duct hypertrophy and [[Liver General Pathology - Pathology#Fibrosis - Repair|fibrosis]] are present.  However, lymphocytic cholangitis does not progress to biliary [[Liver General Pathology - Pathology#Cirrhosis|cirrhosis]].  An immune-mediated aetiology has been postulated but this has not been substantiated to date.  It is rarely associated with [[Pancreatitis - WikiClinical|pancreatitis]], compared to [[Neutrophilic Cholangitis]]

==Diagnosis==

==Diagnosis==

*Antioxidants such as S-adenosylmethionine and vitamin E.

*Antioxidants such as S-adenosylmethionine and vitamin E.

**These are used to counteract the potent oxidising property of bile.

**These are used to counteract the potent oxidising property of bile.

==Prognosis==

==Prognosis==