Changes

==Description==

==Description==

'''Insulinomas''' are slow growing, well-encapsulated, functional tumours of the [[Pancreas - Anatomy & Physiology#Endocrine|beta cells]] of the pancreatic islet cells.  They secrete inappropriately high amount of [[Pancreas - Anatomy & Physiology#Insulin|insulin]] irrespective of the serum glucose level.  They are predominantly malignant (90% of canine insulinomas), with a high metastatic rate to regional lymph nodes, liver and omentum.  60% of isulinomas are carcinomas, which are more likely to be endocrinologically active, the others being adenomas.

'''Insulinomas''' are slow growing, well-encapsulated, functional tumours of the [[Pancreas - Anatomy & Physiology#Endocrine|beta cells]] of the pancreatic islet cells.  They secrete inappropriately high amount of [[Pancreas - Anatomy & Physiology#Insulin|insulin]] irrespective of the serum glucose level.  They are predominantly [[Neoplasia - Pathology#Classification|malignant]] (90% of canine insulinomas), with a high metastatic rate to regional [[Lymph Nodes - Pathology|lymph nodes]], [[Liver - Anatomy & Physiology|liver]] and omentum.  60% of isulinomas are [[Neoplasia - Pathology#Nomenclature|carcinomas]], which are more likely to be endocrinologically active, the others being adenomas.

==Diagnosis==

==Diagnosis==