172
edits
Changes
→Griseofluvin
==Griseofluvin==
==Griseofulvin==
* This drug is a natural antifungal produced by ''Penicillium griseofulvum'', it works by interacting with fungal microtubules and halts mitosis and so is '''fungistatic'''.
* This drug is a natural antifungal produced by ''Penicillium griseofulvum'', it works by interacting with fungal microtubules and halts mitosis and so is '''fungistatic'''.
* It has a narrow spectrum of activity only really inhibiting the growth of dermatophytes.
* It has a narrow spectrum of activity only really inhibiting the growth of dermatophytes.
* It is eliminated by hepatic metabolism.
* It is eliminated by hepatic metabolism.
* It is '''teratogenic''', so should never be given to pregnant animals. It can exacerbate liver damage and so function should be monitored. There have been reports in cats of bone marrow toxicity.
* It is '''teratogenic''', so should never be given to pregnant animals. It can exacerbate liver damage and so function should be monitored. There have been reports in cats of bone marrow toxicity.
==Flucytosine==
==Flucytosine==