Changes

Acepromazine potentiates the actions of several other drugs. These include [[Local Anaesthetics|local anaesthetic agents]], general anaesthetics and opioids (forming the principal of neurolept analgesia). Administration of the drug may also lower the threshold for seizures but, interestingly, acepromazine may be used as an anticonvulsant. ACP is also anti-emetic.

Acepromazine potentiates the actions of several other drugs. These include [[Local Anaesthetics|local anaesthetic agents]], general anaesthetics and opioids (forming the principal of neurolept analgesia). Administration of the drug may also lower the threshold for seizures but, interestingly, acepromazine may be used as an anticonvulsant. ACP is also anti-emetic.

Use of acepromazine is contra-indicated in breeding stallions, as it may cause penis protrusion and priapism. Boxers and giant breeds of dog require lower doses of the drug.

Use of acepromazine is contra-indicated in breeding stallions, as it may cause penis protrusion and priapism. In Boxers spontaneous fainting and syncope can occur due to sinoatrial block caused by excessive vagal tone, so acepromazien should be given in low doses or avoided in this breed. Giant breeds of dog require lower doses of the drug.

===Methotrimeprazine===

===Methotrimeprazine===