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| * DOES NOT REFER TO THE THE FAT STORES OF THE BODY! | | * DOES NOT REFER TO THE THE FAT STORES OF THE BODY! |
| + | ** Fatty substances accumulate or increase within the cytoplams of specific cells. |
| + | ** In some instances, the fat stores may be involved in the transfer of fat to these specific cells. |
| * Cellular fatty change is an important intracellular abnormality. | | * Cellular fatty change is an important intracellular abnormality. |
| ** Principally concerns the intracellular fat in hepatocytes. | | ** Principally concerns the intracellular fat in hepatocytes. |
| + | * Fatty change is commonly seen in three organs of the body. |
| + | ** Prinicpally in the '''liver'''. |
| + | ** Also in the '''kidney''' and the '''heart'''. |
| + | ** This is because these organs are either: |
| + | *** Involved in the metabolism of fat, or |
| + | *** Dependant upon lipids as an energy source. |
| + | * Fatty change can be readily recognised at post-mortem. |
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− | | + | ====Appearance of Fatty Change==== |
− | This is the accumulation or increase of fatty substances within the cytoplasm of specific
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− | cells and does not refer to the fat stores of the body, although in some cases they may be
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− | involved in the transfer of fat to these specific cells.
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− | Fatty change is commonly seen in three organs of the body, i.e. principally in the liver but | |
− | also the kidney and heart; mainly because these organs are either involved in the metabolism
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− | of fat or dependant upon lipids as an energy source.
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− | It is an important condition, because it is something that can readily be recognised at postmortem
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− | examination.
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− | Appearance of fatty change
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| Liver: this is the predominant organ | | Liver: this is the predominant organ |
| involved in fatty change. | | involved in fatty change. |