Changes

===Hyaline Degeneration===

===Hyaline Degeneration===

Hyaline degeneration - a descriptive term meaning 'glassy'' and applied to several

* The term "hyaline degeneration" is applied to several types of degeneration or infiltration.

types of degeneration or infiltration. Some are extracellular e.g. protein hyaline casts in the

** "Hyaline" is a descriptive term meaning 'glassy''.

renal tubules, while others are intracellular e.g. hyaline degeneration of skeletal muscle. The

*** Used in pathology when structureless material appears in section, and stains red with eosin

word hyaline is used in pathology when material appears structureless in section and stains

**** Describes a variety of conditions in which structureless materials are present.

red with eosin. Hyaline degeneration is really a descriptive term of a variety of

conditions in which structureless materials are present.

** '''Extracellular'''

Instances of 'hyaline' degeneration:

*** Protein hyaline casts in the renal tubules.

a. renal intratubular casts from excessive protein passing through glomerulus: When fresh

**** From excessive protein passing through glomerulus.

urine is examined under the microscope, they may be seen as elongated glassy tubes.

**** When fresh urine is examined under the microscope, casts may be seen as elongated glassy tubes.  

b. proteinaceous effusions into pulmonary alveoli are known as hyaline membranes: they

prevent gaseous exchange.

**** Proteinaceous effusions into pulmonary alveoli

c. hyaline degeneration of muscle in deficiency of Vit. E/ Selenium.

**** Prevent gaseous exchange.

Two forms of hyaline change deserve mention on their own. One is fibrinoid degeneration

*** Hyaline degeneration of skeletal muscle.  

and the other is amyloid infiltration.

**** In vitamin E/ selenium deficiency.

* There are two forms of hyaline degeneration that deserve their own mention.

** Fibrinoid degeneration.

** Amyloid infiltration.

====Fibrinoid Degeneration====

====Fibrinoid Degeneration====