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Special:MobileDiff/5394
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General Pathology
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Revision as of 10:01, 20 August 2007
925 bytes added
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10:01, 20 August 2007
→Cellular Inclusions
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===Cellular Inclusions===
===Cellular Inclusions===
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====Viruses====
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* Either in the nucleus or cytoplasm.
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====Storage Products====
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* Due to '''hereditary storage diseases''' in which there is a missing or defectivecellular enzyme. There are many types known in domestic animals.
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** Break down/ build up of intracellular substances is halted.
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*** The intermediate substance accumulates in the lysosomes.
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** Affects all tissues
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*** The central nervous system is particularly vulnerable.
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* Due to '''age'''
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** Lysosomes will accumulate non-degradable products
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*** E.g. lipofuscin - the 'ageing' or 'wear and tear pigment'.
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**** Cmmonly seen in middle-aged cats in the hepatocytes nearest the centrilobular veins.
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====Intracellular Bacteria====
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* For example, [[Mycobacteria spp.|''Mycobacterium tuberculosis'']] in macrophages.
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====Protein Accumulation====
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* In the renal tubular epithelium.
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* Occurs when there is leakage of protein out through a damaged glomerulus.
==Necrosis==
==Necrosis==
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