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The phenothiazines are also antagonists at α1 adrenergic receptors, histamine H1 receptors, muscarinic cholinergic receptors and serotonin 5-HT2 receptors, explaining a number of prominent '''side effects''', including decreased hematocrit (α1 adrenoceptors in the splenic capsule), decreased total peripheral resistance (hypotension, α1 adrenoceptors in the vasculature) and penile prolapse (priapism). Hypotension can be profound, particularly in animals with high levels of circulating catecholamines (stress).
 
The phenothiazines are also antagonists at α1 adrenergic receptors, histamine H1 receptors, muscarinic cholinergic receptors and serotonin 5-HT2 receptors, explaining a number of prominent '''side effects''', including decreased hematocrit (α1 adrenoceptors in the splenic capsule), decreased total peripheral resistance (hypotension, α1 adrenoceptors in the vasculature) and penile prolapse (priapism). Hypotension can be profound, particularly in animals with high levels of circulating catecholamines (stress).
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'''ACP does NOT produce analgesia''' and has a relatively long duration and relatively slow onset of effect, e.g. 20 to 30 minutes. ACP should be used with caution in male donkeys (priapism) and in animals with impaired hepatic function (potentially prolonged effects). ACP should not be used in breeding stallions. '''The neuroleptanalgesic combination of ACP with the potent opioid analgesic etorphine should NOT be used in donkeys.'''
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'''ACP does NOT produce analgesia''' and has a relatively long duration and relatively slow onset of effect, ''e.g.'' 20 to 30 minutes. ACP should be used with caution in male donkeys (priapism) and in animals with impaired hepatic function (potentially prolonged effects). ACP should not be used in breeding stallions. '''The neuroleptanalgesic combination of ACP with the potent opioid analgesic etorphine should NOT be used in donkeys.'''
    
==[[Benzodiazepines|Diazepam]]==
 
==[[Benzodiazepines|Diazepam]]==
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