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*Histopathology can establish a positive diagnosis from endoscopic biopsy or surgical biopsy. Negative histology does not rule out cryptosporidiosis because of the non-uniform distribution of cryptosporidia.
*Histopathology can establish a positive diagnosis from endoscopic biopsy or surgical biopsy. Negative histology does not rule out cryptosporidiosis because of the non-uniform distribution of cryptosporidia.
[[Image:Clinical_cryptosporidiosis_snow_corn_snake.jpg|350px|thumb|right]]
==Therapy==
==Therapy==
Treatment can be supportive but death usually occurs from a few months to a year after the clinical signs are first noticed. Treatment with immunoglobulins may be helpful. Euthanasia may be the most realistic option. If not, strict quarantine of any infected snakes is very important to stop the spread of infection. Disinfection of contaminated areas can be carried out with 5% ammonia or 10% formalin. Hypochlorite at 3% is not effective.
Treatment can be supportive but death usually occurs from a few months to a year after the clinical signs are first noticed. Treatment with immunoglobulins may be helpful. Euthanasia may be the most realistic option. If not, strict quarantine of any infected snakes is very important to stop the spread of infection. Disinfection of contaminated areas can be carried out with 5% ammonia or 10% formalin. Hypochlorite at 3% is not effective.