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Created page with '===''Campylobacter jejuni''=== *Widespread on farms - hyperendemic *Carried as commensals in intestines of cattle, sheep…'
===[[Intestine Pathogens - Pathology#Campylobacter jejuni|''Campylobacter jejuni'']]===
*Widespread on farms - hyperendemic
*Carried as commensals in intestines of cattle, sheep, dogs, wild birds and especially chickens
*Farm animals regularly exposed via faecal-oral route; maternal antibody protects while active immunity develops
*Animals with little exposure are very susceptible, e.g. humans, pets
*Most chicken carcasses contaminated, leading to food poisoning and enterocolitis in people from uncooked meat
*Colonisation, attachment and invasion of colonic enterocytes; toxin production
*Necrosis of colonic absorptive epithelial cells, erosion of mucosa, crypt abscesses, inflammatory infiltrate of [[Neutrophils - WikiBlood|neutrophils]] into mucosa causes colitis
*Enteritis and diarrhoea in susceptible dogs; treatment with enrofloxacin
*Causes abortion in ewes
*Usually asymptomatic infections in chickens and turkeys, but occasional outbreaks of avian hepatitis occur with decreased egg production, loss of condition, haemorrhage and necrosis of liver; phase contrast microscopy demonstrates curved rods in bile; in-feed dihydrostreptomycin sulphate in outbreak
*Implicated in [[Intestines Catarrhal Enteritis - Pathology#Undifferentiated Neonatal Calf Diarrhoea|undifferentiated neonatal calf diarrhoea]], a mixed viral enteritis in calves[[Category:Campylobacter_species]][[Category:Dog]][[Category:Cattle]][[Category:Sheep]]
*Widespread on farms - hyperendemic
*Carried as commensals in intestines of cattle, sheep, dogs, wild birds and especially chickens
*Farm animals regularly exposed via faecal-oral route; maternal antibody protects while active immunity develops
*Animals with little exposure are very susceptible, e.g. humans, pets
*Most chicken carcasses contaminated, leading to food poisoning and enterocolitis in people from uncooked meat
*Colonisation, attachment and invasion of colonic enterocytes; toxin production
*Necrosis of colonic absorptive epithelial cells, erosion of mucosa, crypt abscesses, inflammatory infiltrate of [[Neutrophils - WikiBlood|neutrophils]] into mucosa causes colitis
*Enteritis and diarrhoea in susceptible dogs; treatment with enrofloxacin
*Causes abortion in ewes
*Usually asymptomatic infections in chickens and turkeys, but occasional outbreaks of avian hepatitis occur with decreased egg production, loss of condition, haemorrhage and necrosis of liver; phase contrast microscopy demonstrates curved rods in bile; in-feed dihydrostreptomycin sulphate in outbreak
*Implicated in [[Intestines Catarrhal Enteritis - Pathology#Undifferentiated Neonatal Calf Diarrhoea|undifferentiated neonatal calf diarrhoea]], a mixed viral enteritis in calves[[Category:Campylobacter_species]][[Category:Dog]][[Category:Cattle]][[Category:Sheep]]