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Created page with '*Formerly known as ''Bacteroides'' *Characteristics: **Large Gram negative rods with terminal swellings **Long polar fimbriae **16 antigenic types of fimbriae - used to different…'
*Formerly known as ''Bacteroides''
*Characteristics:
**Large Gram negative rods with terminal swellings
**Long polar fimbriae
**16 antigenic types of fimbriae - used to differentiate strains antigenically
**All strains possess same O antigen
**Colonies of virulent strains have a dark central zone, a pale granular middle zone and an irregular periphery
**Strains detected by ELISA and PCR
**Thermostable proteases and elastase contribute to pathogenesis
**Keratinolytic proteases required for virulence
**Fimbriae required for adhesion to hoof
**Primary pathogen of epidermal tissues of hoof of ruminants, suriving briefly in the envionment
**Passed from animal to animal
**Causes foot rot in sheep along with other bacteria
*Ovine footrot:
**Contagious, economically important disease
**Wet pasture and hydrated stratum corneum leads to colonisation by Gram positive cocci and [[Arcanobacter pyogenes|''Arcanobacter pyogenes'']], followed by ''F. necrophorum''; addition of ''D. nodosus'' causes footrot
**Can lead to loss of hoof
*Immunity:
**Homologous antibody to fimbrial antigen prevents adhesion and protects against footrot
**Antibody must penetrate the epidermal layers and reach adequate concentration on the skin surface
**Vaccine available
[[Category:Pathogenic_anaerobic_non-spore-forming_Gram-negative_bacteri]][[Category:Sheep]]
*Characteristics:
**Large Gram negative rods with terminal swellings
**Long polar fimbriae
**16 antigenic types of fimbriae - used to differentiate strains antigenically
**All strains possess same O antigen
**Colonies of virulent strains have a dark central zone, a pale granular middle zone and an irregular periphery
**Strains detected by ELISA and PCR
**Thermostable proteases and elastase contribute to pathogenesis
**Keratinolytic proteases required for virulence
**Fimbriae required for adhesion to hoof
**Primary pathogen of epidermal tissues of hoof of ruminants, suriving briefly in the envionment
**Passed from animal to animal
**Causes foot rot in sheep along with other bacteria
*Ovine footrot:
**Contagious, economically important disease
**Wet pasture and hydrated stratum corneum leads to colonisation by Gram positive cocci and [[Arcanobacter pyogenes|''Arcanobacter pyogenes'']], followed by ''F. necrophorum''; addition of ''D. nodosus'' causes footrot
**Can lead to loss of hoof
*Immunity:
**Homologous antibody to fimbrial antigen prevents adhesion and protects against footrot
**Antibody must penetrate the epidermal layers and reach adequate concentration on the skin surface
**Vaccine available
[[Category:Pathogenic_anaerobic_non-spore-forming_Gram-negative_bacteri]][[Category:Sheep]]