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| − | ===[[Respiratory Bacterial Infections - Pathology#Contagious bovine pleuropneumonia (CBPP)|Contagious bovine pleuropneumonia]]===
| + | [[Mycoplasma mycoides subsp. mycoides]] |
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| − | *[[Respiratory Bacterial Infections - Pathology#Contagious bovine pleuropneumonia (CBPP)|Contagious bovine pleuropneumonia]] is caused by ''M. mycoides'' subsp. ''mycoides'' small colony type
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| − | *A severe contagious disease of cattle
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| − | *Endemic in Africa, the Middle East and Asia
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| − | *Aerosol transmission by close contact with clinically or subclinically affected animals
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| − | *Severity depends on strain and host susceptibility
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| − | *Slow spread of infection
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| − | *50% morbidity; mortality rate high in severe outbreaks
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| − | *Large colony type causes pleuropneumonia, mastitis, septicaemia and polyarthritis
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| − | *Clinical signs
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| − | **Acute onset fever, anorexia, depression, lowered milk yield, hyperpnoea, coughing and a mucopurulent nasal discharge
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| − | **Dyspnoea occurs with abducted elbows and extended necks and an expiratory grunt
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| − | **Can be fatal within 1-3 weeks
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| − | **Calves may suffer from [[Joints Inflammatory - Pathology#In Cattle|arthritis]], synovitis and endocarditis
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| − | *Gross pathology
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| − | **Marbled appearance to lungs with consolidated grey and red lobules separated by emphysematous areas
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| − | **Serofibrinous pleural fluid
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| − | **Necrotic foci surrounded by fibrous capsules in chronic cases act as source of infection
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| − | *Diagnosis
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| − | **Clinical signs and post-mortem appearance
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| − | **PCR on pleural fluid, lung tissue, regional lymph nodes or bronchoalveolar lavage fluid
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| − | **Fluorescent antibody test
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| − | **Serological tests such as serum agglutination, haemagglutination, complement fixation, ELISA
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| − | *Treatment and control
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| − | **Slaughter of affected cattle in counries where the disease is exotic
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| − | **Movement restrictions, quaranteen and slaughter of carrier animals in endemic countries
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| − | **Vaccination in endemic regions
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