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*Early stages (only first few days) may show [[Degenerations and Infiltrations - Pathology#Cellular Inclusions|intracellular inclusions]] in the respiratory mucosal epithelial cells
 
*Early stages (only first few days) may show [[Degenerations and Infiltrations - Pathology#Cellular Inclusions|intracellular inclusions]] in the respiratory mucosal epithelial cells
 
*Leading to neutrophilic inflammation of varying severity.... serous -> catarrhal -> purulent  
 
*Leading to neutrophilic inflammation of varying severity.... serous -> catarrhal -> purulent  
*With secondary bacterial infection (eg: [[Pasteurella species and Mannheimia haemolytica|Pasturella spp.]], [[:Category:Mycoplasmas|Mycoplasma spp.]], [[Fusobacterium|Fusobacterium necrophorum]]) can lead to fibrinous to necrotizing inflammation; mucosal sloughing, ulceration... pyrexia, dyspnoea ... [[Lungs Inflammatory - Pathology#Aspiration pneumonia|inhalation pneumonia]]... death
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*With secondary bacterial infection (eg: [[:Category:Pasteurella and Mannheimia species|Pasturella spp.]], [[:Category:Mycoplasmas|Mycoplasma spp.]], [[Fusobacterium|Fusobacterium necrophorum]]) can lead to fibrinous to necrotizing inflammation; mucosal sloughing, ulceration... pyrexia, dyspnoea ... [[Lungs Inflammatory - Pathology#Aspiration pneumonia|inhalation pneumonia]]... death
 
*Underlying hyperaemic inflammatory response
 
*Underlying hyperaemic inflammatory response
 
*Can become latent following primary infection
 
*Can become latent following primary infection
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*Causative agent: [[Paramyxoviridae#Bovine Parainfluenza - 3 (PI-3)|parainfluenza- 3 virus]] (PI3)
 
*Causative agent: [[Paramyxoviridae#Bovine Parainfluenza - 3 (PI-3)|parainfluenza- 3 virus]] (PI3)
 
*On its own causes [[Nasal Cavity Inflammatory - Pathology#Infectious causes of rhinitis|rhinitis]]  
 
*On its own causes [[Nasal Cavity Inflammatory - Pathology#Infectious causes of rhinitis|rhinitis]]  
*Often part of multi-aetiology disease complex (e.g. [[Respiratory Bacterial Infections - Pathology#Enzootic pneumonia of calves|Enzootic pneumonia of calves]]), often followed by [[Pasteurella species and Mannheimia haemolytica|''Pasteurella sp.'']] obscuring viral origin
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*Often part of multi-aetiology disease complex (e.g. [[Respiratory Bacterial Infections - Pathology#Enzootic pneumonia of calves|Enzootic pneumonia of calves]]), often followed by [[:Category:Pasteurella and Mannheimia species|''Pasteurella sp.'']] obscuring viral origin
 
*Replicates in airway epithelial cells and results in an initial [[Bronchi and Bronchioles Inflammatory - Pathology#Infectious causes of bronchitis or bronchiolitis|bronchitis -> bronchiolitis]] -> extension into [[Lungs Inflammatory - Pathology#Infectious causes of pneumonia|alveoli]], causing [[Lungs Inflammatory - Pathology#Bronchointerstitial pneumonia|bronchointerstitial pneumonia]]  
 
*Replicates in airway epithelial cells and results in an initial [[Bronchi and Bronchioles Inflammatory - Pathology#Infectious causes of bronchitis or bronchiolitis|bronchitis -> bronchiolitis]] -> extension into [[Lungs Inflammatory - Pathology#Infectious causes of pneumonia|alveoli]], causing [[Lungs Inflammatory - Pathology#Bronchointerstitial pneumonia|bronchointerstitial pneumonia]]  
 
*Early stages may show [[Degenerations and Infiltrations - Pathology#Cellular Inclusions|intracytoplasmic inclusions]]
 
*Early stages may show [[Degenerations and Infiltrations - Pathology#Cellular Inclusions|intracytoplasmic inclusions]]
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