*Occurs spontaneously in adult in any disorder that disrupts normal reflex involved in swallowing either peripheral or central.
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*These can include:
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**Viral encephalitides
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**Peripheral neuropathies
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***Degeneration or inactivity of local myenteric nerve plexuses (Auerbach’s plexuses),
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***or to lesions in the vagus nerve or the central nucleus in the medulla of the brain which supply the [[Oesophagus - Anatomy & Physiology|oesophagus]].
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**Poisonings such as:
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***Lead
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***Tetanus
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***Botulism
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**Myopathies.
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*The result is the presence of a hypotonic [[Oesophagus - Anatomy & Physiology|oesophagus]] in which food accumulates causing distension
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*Usually the thoracic oesophagus from the thoracic inlet to the diaphragm is affected and grossly the [[Oesophagus - Anatomy & Physiology|oesophagus]] is dilated, thin-walled and hypotonic.