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Created page with '{{review}} Granulomatous inflammation * ''Mucor'', a fungi, invades the rumen wall, e.g. after damage caused by [[Rumenal Acidosis|rumenal …'
{{review}}
Granulomatous inflammation
* ''Mucor'', a fungi, invades the [[The Rumen - Anatomy & Physiology|rumen]] wall, e.g. after damage caused by [[Rumenal Acidosis|rumenal acidosis]].
* Produces chronic ongoing granulomatous rumenitis.
* Difficult to diagnose in life.
* May produce pain and poor growth
* Infective process may penetrate wall and produce peritonitis.
====Pathology====
=====Gross=====
* Thickening and ulceration of mucosal surface of [[The Rumen - Anatomy & Physiology|rumen]].
** Feels like thick leather.
*[[The Rumen - Anatomy & Physiology|Rumen]] wall becomes fibrosed.
=====Histological=====
* Classical granulomatous inflammation
** May have giant cells in addition to sheets of [[Macrophages - WikiBlood|macrophages]].
* Can visualise fungal hyphae in tissue using special stains (PAS),
** Often grow along blood vessels.
*** May cause thrombosis of small blood vessels, leading to further necrosis (infarction) of [[The Rumen - Anatomy & Physiology|rumen]] wall.[[Category:Forestomach_-_Inflammatory_Pathology]][[Category:Cattle]]
Granulomatous inflammation
* ''Mucor'', a fungi, invades the [[The Rumen - Anatomy & Physiology|rumen]] wall, e.g. after damage caused by [[Rumenal Acidosis|rumenal acidosis]].
* Produces chronic ongoing granulomatous rumenitis.
* Difficult to diagnose in life.
* May produce pain and poor growth
* Infective process may penetrate wall and produce peritonitis.
====Pathology====
=====Gross=====
* Thickening and ulceration of mucosal surface of [[The Rumen - Anatomy & Physiology|rumen]].
** Feels like thick leather.
*[[The Rumen - Anatomy & Physiology|Rumen]] wall becomes fibrosed.
=====Histological=====
* Classical granulomatous inflammation
** May have giant cells in addition to sheets of [[Macrophages - WikiBlood|macrophages]].
* Can visualise fungal hyphae in tissue using special stains (PAS),
** Often grow along blood vessels.
*** May cause thrombosis of small blood vessels, leading to further necrosis (infarction) of [[The Rumen - Anatomy & Physiology|rumen]] wall.[[Category:Forestomach_-_Inflammatory_Pathology]][[Category:Cattle]]