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Created page with '* Affects the '''horse'''. ** Usually young to middle age adults. * Unknown cause. * Is a one-off occurence rather than a herd problem. * As in Johnes Diseaase, there is chroni…'
* Affects the '''horse'''.
** Usually young to middle age adults.
* Unknown cause.
* Is a one-off occurence rather than a herd problem.
* As in Johnes Diseaase, there is chronic ongoing diarrhoea with eventual death.
* Thickening of mucosa is seen mainly in the [[Caecum - Anatomy & Physiology|caecum]] and [[Colon - Anatomy & Physiology|colon]].
** Lamina propria contains granulomatous inflammatory tissue (as in [[Johne's Disease]]).
** Sometimes large numbers of eosinophils are seen.
* Mesenteric lymph nodes are very large.
* At laparotomy lymph node appears like lymphosarcoma (very large).
* Cannot do much to remedy the condition once it has started.
** Progresses to death.
====Proposed Pathogenesis====
* Hypersensitivity reaction to trichoneme parasite?
** Possibly an idiosyncratic response to the encysted larvae.
* Dysbacteriosis or disordered immune response?
[[Category:Enteritis,_Proliferative]][[Category:Horse]]
** Usually young to middle age adults.
* Unknown cause.
* Is a one-off occurence rather than a herd problem.
* As in Johnes Diseaase, there is chronic ongoing diarrhoea with eventual death.
* Thickening of mucosa is seen mainly in the [[Caecum - Anatomy & Physiology|caecum]] and [[Colon - Anatomy & Physiology|colon]].
** Lamina propria contains granulomatous inflammatory tissue (as in [[Johne's Disease]]).
** Sometimes large numbers of eosinophils are seen.
* Mesenteric lymph nodes are very large.
* At laparotomy lymph node appears like lymphosarcoma (very large).
* Cannot do much to remedy the condition once it has started.
** Progresses to death.
====Proposed Pathogenesis====
* Hypersensitivity reaction to trichoneme parasite?
** Possibly an idiosyncratic response to the encysted larvae.
* Dysbacteriosis or disordered immune response?
[[Category:Enteritis,_Proliferative]][[Category:Horse]]