Changes

* [[Carcinoma#Pancreatic|Carcinomas]]

* [[Carcinoma#Pancreatic|Carcinomas]]

* Adenocarcinomas

* Adenocarcinomas

* [[Pancreas Hyperplastic and Neoplastic - Pathology #Adenomas|Adenomas]]

* [[Adenoma#Pancreatic|Adenomas]]

It is important to make the distinction between pancreatic neoplasia and [[Pancreas Hyperplastic and Neoplastic - Pathology #Nodular hyperplasia|pancreatic nodular hyperplasia]] which frequently occurs in older dogs and cats and is non-significant.

It is important to make the distinction between pancreatic neoplasia and [[Pancreas - Nodular Hyperplasia|pancreatic nodular hyperplasia]] which frequently occurs in older dogs and cats and is non-significant.

==Signalment==

==Signalment==

[[Pancreas Hyperplastic and Neoplastic - Pathology #Carcinomas|Carcinomas]]:

[[Carcinoma#Pancreatic|Carcinomas]]:

* Usually female dogs with a mean age of 10 years

* Usually female dogs with a mean age of 10 years

* Spaniels and Airedale terriers may have breed predispositions

* Spaniels and Airedale terriers may have breed predispositions

==Description==  

==Description==  

Aetiology is idiopathic. [[Pancreas Hyperplastic and Neoplastic - Pathology #Adenomas|Adenomas]], although they do not metastasise and are frequently small and focal, can compress the surrounding pancreas. [[Pancreas Hyperplastic and Neoplastic - Pathology #Carcinomas|Carcinomas]] are aggressive with local invasion of the stomach or duodenum and metastasis to the liver, regional lymph nodes (hepatic and splenic), lungs, periotoneal surface and other abdominal organs usually occurring prior to a diagnosis being reached. Other complications include blockage of the common bile duct and [[Exocrine Pancreatic Insufficiency - WikiClinical|exocrine pancreatic insufficiency]]. [[Pancreatitis - WikiClinical|Pancreatitis]] can also occur where pancreatic atrophy results in tumour necrosis and an inflammatory response.

Aetiology is idiopathic. [[Adenoma#Pancreatic|Adenomas]], although they do not metastasise and are frequently small and focal, can compress the surrounding pancreas. [[Carcinoma#Pancreatic|Carcinomas]] are aggressive with local invasion of the stomach or duodenum and metastasis to the liver, regional lymph nodes (hepatic and splenic), lungs, periotoneal surface and other abdominal organs usually occurring prior to a diagnosis being reached. Other complications include blockage of the common bile duct and [[Exocrine Pancreatic Insufficiency - WikiClinical|exocrine pancreatic insufficiency]]. [[Pancreatitis - WikiClinical|Pancreatitis]] can also occur where pancreatic atrophy results in tumour necrosis and an inflammatory response.