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Major Histocompatability Complexes (view source)
Revision as of 16:22, 12 June 2010
, 16:22, 12 June 2010Text replace - 'Immunoglobulins - WikiBlood' to 'Immunoglobulins'
**Most polymorphic regions of class II are in the alpha 1 and beta 1 domains
**Most polymorphic regions of class II are in the alpha 1 and beta 1 domains
*Most polymorphisms are point mutations
*Most polymorphisms are point mutations
* There are millions of variations in [[Immunoglobulins - WikiBlood|antibodies]] and TCR
* There are millions of variations in [[Immunoglobulins|antibodies]] and TCR
** However, with MHC there is very limited variation between molecules
** However, with MHC there is very limited variation between molecules
*Allelic variation within the MHC molecule occurs at the peptide binding site and on the top or sides of the binding cleft
*Allelic variation within the MHC molecule occurs at the peptide binding site and on the top or sides of the binding cleft