Changes

*Physiological: In resposnse to exercise in athletic animals E.g. racing greyhounds.

*Physiological: In resposnse to exercise in athletic animals E.g. racing greyhounds.

*Pathological:  

*Pathological:  

**'''Concentric''': Due to pressure overload E.g. [[Pericardial - Pathology#Inflammatory-Pericarditis|restrictive pericarditis]].  Thickened chamber walls with a decreased chamber lumen, often will result in myocardial hypoxia.  Fibrosis of the myocardium will restrict chamber expansion and filling at diastole leading to '''diastolic failure'''.

**'''Concentric''': Due to pressure overload E.g. [[Pericarditis#Inflammatory-Pericarditis|restrictive pericarditis]].  Thickened chamber walls with a decreased chamber lumen, often will result in myocardial hypoxia.  Fibrosis of the myocardium will restrict chamber expansion and filling at diastole leading to '''diastolic failure'''.

**'''Eccentric''': Due to volume overload.  Increased wall thickness, which may be variable, with a dilated chamber.  E.g. mitral regurgitation will result in eccentric hypertrophy of the left atrium.

**'''Eccentric''': Due to volume overload.  Increased wall thickness, which may be variable, with a dilated chamber.  E.g. mitral regurgitation will result in eccentric hypertrophy of the left atrium.