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| − | ===Hyaline degeneration=== | + | ===[[Hyaline Degeneration]]=== |
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| − | Hyalisation of muscle fibrils of skeletal, intercostal, diaphragmatic and cardiac muscles. Histologically there is '''[[Zenker Degeneration - Pathology|Zenker degeneration]]''' and occasionally also '''[[Myocardial - Pathology#Mineralisation|dystrophic calcification]]'''.
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| − | Grossly the condition is seen as grey/yellow streaks on the innermost part of the myocardium.
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| − | The condition is associated with '''Vitamin/Selenium deficiency'''. Also known as [[Muscles Degenerative - Pathology#Nutritional myopathy|'''nutritional myopathy''']] or '''[[White Muscle Disease - Pathology|White muscle disease]]'''.
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| − | The myocardium of the left ventricle is most affected as it has the largest metabolic demand and so the largest production of anti-oxidants and the greatest need for Vitamin E/Selenium. This manifests clinically as left sided heart failure with clinical signs:
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| − | *Pulmonary oedema.
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| − | Also:
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| − | *Acute ataxia and collapse with the skeletal muscles affected.
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| − | Also associated with a diet over-rich in unsaturated fatty acids seen in pigs (Vitamin E/Selenium unavailable as used up by the unsaturated fats).
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| | ===Lipofuscinosis=== | | ===Lipofuscinosis=== |